Bayesian adaptive basket trial design using model averaging

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Predicting waste generation using Bayesian model averaging

A prognosis model has been developed for solid waste generation from households in Hoi An City, a famous tourist city in Viet Nam. Waste sampling, followed by a questionnaire survey, was carried out to gather data. The Bayesian model average method was used to identify factors significantly associated with waste generation. Multivariate linear regression analysis was then applied to evaluate th...

متن کامل

Improving Predictions Using Ensemble Bayesian Model Averaging

We present ensemble Bayesian model averaging (EBMA) and illustrate its ability to aid scholars in the social sciences to make more accurate forecasts of future events. In essence, EBMA improves prediction by pooling information from multiple forecast models to generate ensemble predictions similar to a weighted average of component forecasts. The weight assigned to each forecast is calibrated v...

متن کامل

Bayesian response-adaptive designs for basket trials.

We develop a general class of response-adaptive Bayesian designs using hierarchical models, and provide open source software to implement them. Our work is motivated by recent master protocols in oncology, where several treatments are investigated simultaneously in one or multiple disease types, and treatment efficacy is expected to vary across biomarker-defined subpopulations. Adaptive trials ...

متن کامل

Bayesian Adaptive Sampling for Variable Selection and Model Averaging

For the problem of model choice in linear regression, we introduce a Bayesian adaptive sampling algorithm (BAS), that samples models without replacement from the space of models. For problems that permit enumeration of all models BAS is guaranteed to enumerate the model space in 2p iterations where p is the number of potential variables under consideration. For larger problems where sampling is...

متن کامل

Bayesian Additive Regression Trees using Bayesian model averaging

Bayesian Additive Regression Trees (BART) is a statistical sum of trees model. It can be considered a Bayesian version of machine learning tree ensemble methods where the individual trees are the base learners. However for datasets where the number of variables p is large (e.g. p > 5, 000) the algorithm can become prohibitively expensive, computationally. Another method which is popular for hig...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Biostatistics

سال: 2019

ISSN: 1465-4644,1468-4357

DOI: 10.1093/biostatistics/kxz014